NIIMBL-BioPhorum Buffer Stock Blending (BSB) System: How BioPhorum is Advancing the Buffer Manufacturing Processes

NIIMBL-BioPhorum Buffer Stock Blending (BSB) System: How BioPhorum is Advancing the Buffer Manufacturing Processes

07/16/2020, 10:15 AM - 11:00 AM

Stage 3, Booth 1877, Exhibit Hall
Buffer solutions are a critical piece of the manufacturing process for therapeutic proteins and other biomolecules. The traditional way to make and use buffers is space- and resource-intensive, creating operational bottlenecks that impact efficiencies and costs. BioPhorum Operations Group, in collaboration with the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), has developed a buffer prep work stream for biotech facilities to overcome those common challenges. The full-scale, prototype buffer stock blending skid can potentially significantly reduce capital investment and manual operation costs, reduce the number and volume of buffer, and decrease time for buffer manufacturing. It has been designed and built by a cross-functional team including Rockwell Automation. The open-source model provides a flexible solution using mass flow control for small batch process to provide an on-demand supply of buffer solutions directly to the biomanufacturing proces


  • Doan Chau


    Life Sciences Global Industry Technical Consultant

    Rockwell Automation

    Industry Technical Consultant specializing in Life Sciences Process Automation. I have over 10+ years experience as an end user/system owner for...


  1. Objective 1. Raise awareness and educate about BioPhorum and its mission to facilitate collaboration between biomanufacturers and suppliers to accelerate the pace of change in the industry 2. Articulate the problems we are solving by collaborating in this way and explain why this buffer prep skid is important in the advancement of manufacturing in this space 3. Explore the future of advanced manufacturing: Where are we going next?

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