Continuous Aseptic Manufacturing Using Spray Freeze Drying: Equipment, Process and Product Considerations

Continuous Aseptic Manufacturing Using Spray Freeze Drying: Equipment, Process and Product Considerations

04/02/2019, 1:15 PM - 2:00 PM

Javits Conventions Center - Stage 2, Booth 1577, Exhibit Hall
Language:
English
Freeze drying has traditionally been a batch process making it both time consuming and energy intensive. While the use of new process analytical technology has aided in process understanding, most processes are run conservatively, making it inherently inefficient. It has been identified that poor thermal contact between the shelf and the containment is the rate limiting resistance to heat transfer. Moreover, the drying rate in such a configuration is a function of the coldest front in the product volume, the sublimation front. There is a need to re-think the heat and mass transfer for making the process more efficient. The current technology focuses on bringing to the market a robust yet gentle continuous aseptic process for spray freeze-drying with an eye toward achieving high throughput/ high cycle efficiency. Further, the talk will focus on providing equipment, process and product considerations in using such a technology.

Contributors

  • Arnab Ganguly

    Speaker

    Technology Manager

    IMA Life

    Arnab received a PhD in the School of Aeronautics & Astronautics at Purdue University in 2014 with a focus on modeling low-pressure water-vapor flows...

Type of Session

  1. Type of Session
    Session

Categories

  1. Track
    Optimizing Facilities through Innovation & Technologies

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