Endotoxin Remediation Strategies

Endotoxin Remediation Strategies

04/19/2018, 10:30 AM - 11:15 AM

Technical Conference Stage 4, Booth 1477, Exhibit Hall
Language:
English

Microbial contamination of process equipment and water systems is a concern for pharmaceutical, biopharmaceutical and medical device industries. Microbial contamination with Gram negative bacteria, often found in low level biofilm populations, can lead to out-of-specification endotoxin levels in intermediate and final product. Endotoxin contamination can lead to costly delays in production, product loss and regulatory issues. This presentation will review common endotoxin remediation steps as well as discuss biofilm remediation strategies and preventive maintenance activities of stainless steel surfaces which are often identified as the root cause of elevated endotoxin levels. Several case studies from different manufacturing processes will also be shared during the presentation.

Contributors

  • Paul Lopolito

    Speaker

    Technical Services Senior Manager

    STERIS Corporation

    Paul Lopolito is a senior technical services manager for the Life Sciences Division of STERIS Corporation (Mentor, Ohio). He currently provides...

Type of Session

  1. Type of Session
    Session

Learning Objectives

  1. Learning Objectives 1. Review sources of endotoxin contamination and potential risk to the patient 2. Discuss common strategies to reduce endotoxin levels from surfaces and liquids 3. Share multiple case studies that utilize different strategies to remediate endotoxin contamination

Categories

  1. Track
    Risk Management

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